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Not Sickening Yourself with Hangover


Expensive, hard on the body, interfering with REM sleep, perhaps alcoholic beverages are better consumed in smaller servings, less often, sparingly, earlier in the day, only until buzzed, & maybe getting drunk with too much also very unwise! Consider the RDA for ethanol & how brewing yeast kicked off the bioscience & lifescience revolutions. 


I think its better to drink slowly for enjoyment of the flavors & to savor that fun buzz ^^ A wise drinker drinks with moderation, for enjoyment, on occasion, with friends & flavor to savor in memories made of good times spend with friends!

I like beer, wine, spirits. I even regularly think about building or buying a still, about gin & tonic, about IPA, lager beers, about tasty wine. I like whisky, bourbon, vodka, dry gin, dry wine, hoppy beer, stuff with more flavor, even sour beers are interesting ^^ Cheers!

I am not against consuming alcoholic beverages! But, maybe less is more, perhaps having 2 drinks is better than 5, perhaps only drinking 3 days per week better than everyday! I don't think most adult men are going to be harmed by having a beer at the Saturday barbecue event they hold with their buddies & friends on the weekend. I am not some kind of teetotaler zealot or part of the teetotalism movement where its practitioners abstain from all forms of alcohol consumption.

Consider that hangovers are caused by dehydration, that the costs of expensive liquor, wine & beer bad for your budget, that ethanol interferes with your sleep architecture & stresses out your liver cells, makes you have to pee more in the night & to avoid a hang over you have to drink a bunch of extra water, which makes the night time urination issue worse.

Is alcohol really so bad for your body to justify the surgeon general putting high contrast warning labels about the negative health effects of drinking alcoholic beverages on the bottles & packages. Probably, consider what drunk drivers end up doing because of their impaired judgment.

Drink to be merry & not to be drunk the wisdom the Bible shares about drinking alcoholic beverages, but I have another idea. Drink less so you do not weaken & sicken yourself. Sicken yourself with alcohol. But Aaron, when the body consumes carbs they ferment in the gut and produce ethanol & CO2 so you burb, say beer belly buddy, & this allows alcohol to enter the blood stream naturally when people eat common popular foods. Ok, I get it, but the dose different & the dose of ethanol is what makes the difference. Just like 1 shot of espresso different than a quad shot!

Think about how adding milk to the espresso makes a latte by changing the fluid volume & adding all sorts of other substances to tame the intense espresso flavors to something more palatable & enjoyable to others, thus the popularity of cappuccino & latte drinks, swelled ice coffee drinks & similar from Starbucks that are trendy & that sell well worldwide. I learned that instant coffee made of freeze dried coffee making a comeback with younger people who do not know about premium coffee or espresso or other complicated to make coffee drinks ^^ but who also do not want that bitter acidic over-brewed battery acid coffee made from commercial pre-ground coffee can coffee's made by huge corporations in high volumes, popular with peoples grandparents, who drink pots of this mediocre coffee all day long. My grandpa, Wesley, used to drink 20+ cups of coffee, God rest his soul!

Treat yourself as a reward after being productive all week, not to close to bedtime either. Give your body a few hours to metabolize your drinks before going to bed for the night! I drank a 24 oz 8.1% beer at about 5:05pm a few days ago & it knocked me out. I feel asleep on the floor shortly after the peak effects of the ethanol were noticed. Admittedly I had been using espresso shots to cover up the accumulated sleep debt & tiredness associated with sleep debt, so what the GABA receptor agonist ethanol did was enable me to catch a badly needed nap, even though I still probably had a fair amount of caffeine in my system.

Ethanol consumption creates oxidative stress on the body, just like sugars. Sugars are the new alcohol, since alcohol losing popularity with the general public sorta like smoking cigarettes did in the 1990's. The trending beverage with millennials Redbull & other energy drinks with B-vitamins & caffeine from several different botanical sources. Some energy drinks have 400mg of caffeine the entire RDA for adults according to WHO or the world health organization. Other countries like Italy, where espresso was developed, recommend a maximum daily caffeine intake of 300mg, so what is an effective RDA for ethanol? Who knows? A few grams perhaps, I don't know. Lets consider the alcohol content of a standard drink consisting of 1.5 shots of 40% hard alcohol, 12 oz of 6% beer or 5 oz of 14% wine

Ethanol Dose Math ( 1 standard drink )

1.5 fl.oz or 44ml X 0.40 "80 proof" = 17.6ml or 0.6 fluid ounces ethanol or about 17 grams et-oh

12 fl.oz or 354ml X 0.06 "12 proof" = 21.2ml or 0.71 fluid ounces of ethanol or about 20 grams et-oh

5 fl.oz or 148ml or 0.14 "28 proof" = 20.7 ml or 0.699 fluid ounces of ethanol or about 19 grams et-oh

Few adults are going to get a good buzz from 1 drink, so many will drink 2 or 3 drinks / so something like 5 oz of liquor, 3 beers or 3 glasses of wine / would be a maximum RDA - obviously there is no minimum

No one has to drink alcohol, ethanol or spirits or beer or wine. People like the flavors of these drinks & because they get a buzz from the GABA receptor activation when ethanol enters their blood stream & hits their brains GABA receptors, making it feel a little bit like they are asleep, while they are awake, disinhibiting people by removing some of their mental filters so they lighten up, ease up, relax, able to socialize better at parties where adults drink alcoholic beverages.

Beer popular at scientific conferences, the magic of yeast fermentation so valuable it help fund a tremendous amount of scientific investigation into biochemistry, pharmacology, medicine, infact many essential drugs like insulin are made with GMO yeast, just like brewing beer in large stainless steel vats, large steel vessel called bioreactors, which are just like high capacity fermenting vessels used at large breweries. Thus its cheap to make insulin & Lantus & other analogs of insulin in large volumes, easily scaled with another bioreactor as the GMO yeast, just as brewing yeast, can be cultivated in a sterile room using sterile techniques, to perpetuate the yeast, strain type them, keeping genetic diversity, selectively breeding to create different cultivars.

Special yeast strains were developed to brew spirits, yeast that can survive in fluids with up to 40% ethanol content. Brewing gave rise to a lot of bioscience, biology, in fact the compound microscopes first big applications was to study yeast used in beer making. At the time, it was thought that beer was made of water, malted barely, & hops, as the open vats would intake wild yeasts that blow around in the air naturally. In wine making the yeast on peoples feet stomping the grapes would contribute to the attenuation of fermentation process.

Ethanol

Produced when yeast consumer starches & sugars, its a simple two carbon alcohol, it can be burned in gasohol blends of gasoline & ethanol, including E10, E15, E35, E85 in flex-fuel vehicles, though ethanol contains about 30% less energy than gasoline, so I buy ethanol free gasoline from The Grange in Issaquah Washington, though Pure-gas has a website where you can fine other fueling stations that sell ethanol free gasoline. In pre-2008 vehicles, that were never designed to use E10, they ECU can produce better fuel economy settings with the correct fuel to air ratio & pulse width settings of the fuel injector & ignition timing settings running on straight gasoline 87 octane, regular unleaded gasoline without ethanol. The reformulated fuels mandate was a governmental measure in the United States that resulted in E10 gasoline & now E15 where fermented GMO corn ethanol added to gasoline to reduce the US dependence on foreign oil, since corn ethanol a domestic fuel, ignoring that foreign diesel fuel powered equipment utilized to grow, harvest, move, processes, manufacture, distribute, etc corn ethanol & its an energetic wash when you consider the energy inputs to make corn ethanol vs the usable energy in the ethanol produced, a wash, though it does produce a lot of economic activity & value added job creating activities in the USA/

Ethanol is a polar solvent like water, able to solubilize a wide variety of chemical substances & utilized to produce tinctures, to sterilize surfaces, as hand sanitizers active ingredient in some formulations, as a carrier in perfume & cologne since the ethanol readily holds a mixture of oils & fragrances suspended in a solution that can be dabbed or sprayed to add scents to the body, personal items or clothing. I use small droplets of sandalwood oil in this way, without ethanol. Some varnishes, stains & paints are suspended in solutions that contain ethanol as a solvent. Sometimes neat or pure ethanol used to rinse lab glass & can be used to sterilize skin prior to scalpel cutting, though iodine solutions are superior. Before anesthetics, ethanol was given to patients to intoxicate them prior to painful surgeries, so that they could endure the surgery, which was brutal in this earlier era of medicine.

Ethanol has a lower boiling point than water and higher vapor pressure (evaporates more easily than water) because it does not participate in strong hydrogen bonding like water, the two carbon chain interferes with the intermolecular forces such that ethanol boils at 173.1 F or 78.38 C, vs 100 C or 212 F for waters boiling point respectively.

Ethanol also called ethyl alcohol, grain alcohol, drinking alcohol or sometimes just "alcohol" EtOH, its chemical formula with 2 carbons, 6 hydrogen & 1 oxygen atoms respectively CH3-CH2-OH or C2H5OH or C2H6O / The dhydrogen saturated double carbon chain called ethyl for 2 (methyl is 1), considered volatile (goes from liquid to gas phase easily), its flammable (thus used as an additive fuel oxygenator in ethanol gasoline blends like E85. Ethanol is a clear colorless liquid with a strong floral metallic flavor & odor similar to wine. People consume ethanol for its psychoactive properties as a recreation drug & ethanol is the active component of alcohol drinks, spirts, wine & beer.

From the IUPAC the systematic name Ethanol defined by a chemical compound consisting of an alkyl group with two carbon atoms (prefix "eth-") having a single bong between them and an attached functional hydroxyl group -OH (suffix "-ol") the name "ethyl" assigned 1843 by Justus Liebig, which he named from German "aether" used to describe diethyl either C2H5-O-C2H5, from the Ancient Greek "Aither" for "upper air" and "Hyle" for "substance" or "Upper Air Substance" when combined. Today the word alcohol refers to a wide variety of different chemicals in chemistry as there are many alcohols, though specifically the word commonly used Alcohol refers to the alcohol present in wine or "The alcohol of wine" as was first recorded in 1753.

With up-to 25% of 50 proof, many medication not soluble or insoluble in water are dissolved in ethanol solutions, including pain medications, cough and cold medicines, mouth washes, & ethanol used as preservative in the liquid preparations of more than 700 different medications. 

Different body enzymes break down ethanol into an intermediate called acetaldehyde, a known carcinogen that poses significantly greater toxicity than ethanol itself. Hangover & other unpleasant side effects of drinking alcohol from the formation of acetaldehyde by ALDH or aldehyde dehydrogenase enzymes. Some people have a mutation in the ALDH2 gene that renders this enzyme pathway dysfunctional, which contributes to the alcoholic flush reaction which is from toxic side effects from the acetaldehyde. Even worse, the ADH1B gene codes for increased enzyme activity in 80% of East Asians that improves catalytic conversion of ethanol to acetaldehyde, making the hangover worse faster. 






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